Publications

132 entries « 2 of 3 »

2017

Hughes, Michael P.; Sawaya, Michael R.; Goldschidt, Lukasz; Jose A. ad Cascio Rodriguez, Duilio; Gonen, Tamir; Eisenberg, David S.

Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets Online

bioRxiv 2017.

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de la Cruz, M. Jason; Martynowycz, Michael; Hattne, Johan; Shi, Dan; Gonen, Tamir

A method to minimize condenser lens-induced hysteresis effects in a JEOL JEM-3200FSC microscope to enable stable cryoEM low-dose operations Online

bioRxiv 2017.

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Martynowycz, Michael W.; Glynn, Calina; Miao, Jennifer M.; de la Cruz, M. Jason; Hattne, Johan; Shi, Dan; Cascio, Duilio; Jose, Rodriguez; Gonen, Tamir

MicroED Structures from Micrometer Thick Protein Crystals Online

bioRxiv 2017.

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Krotee, Pascal; Griner, Sarah L; Sawaya, Michael R; Cascio, Duilio; Rodriguez, Jose A; Shi, Dan; Philipp, Stephan; Murray, Kevin; Saelices, Lorena; Lee, Ji; Seidler, Paul; Glabe, Charles G; Jiang, Lin; Gonen, Tamir; Eisenberg, David S

Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors Journal Article

In: J. Biol. Chem., 293 (8), pp. 2888–2902, 2017.

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de la Cruz, M. Jason; Hattne, Johan; Shi, Dan; Rodriguez, Jose A.; Reyes, Francis E.; Gonen, Tamir

Micro- and nanocrystal preparation for MicroED and XFEL serial crystallography by fragmentation of imperfect crystals Online

Nature Protocol Exchange 2017.

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de la Cruz, Jason M; Hattne, Johan; Shi, Dan; Seidler, Paul; Rodriguez, Jose; Reyes, Francis E; Sawaya, Michael R; Cascio, Duilio; Weiss, Simon C; Kim, Sun Kyung; Hinck, Cynthia S; Hinck, Andrew P; Calero, Guillermo; Eisenberg, David; Gonen, Tamir

Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED Journal Article

In: Nat. Methods, 14 (4), pp. 399–402, 2017.

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Krotee, Pascal; Rodriguez, Jose A; Sawaya, Michael R; Cascio, Duilio; Reyes, Francis E; Shi, Dan; Hattne, Johan; Nannenga, Brent L; Oskarsson, Marie E; Philipp, Stephan; Griner, Sarah; Jiang, Lin; Glabe, Charles G; Westermark, Gunilla T; Gonen, Tamir; Eisenberg, David S

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity Journal Article

In: Elife, 6 , 2017.

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Gonen, Tamir (Ed.)

Challenges in Structural Biology Conference

HHMI Janelia Research Campus, 2017.

2016

Nannenga, Brent L; Gonen, Tamir

MicroED opens a new era for biological structure determination Journal Article

In: Curr. Opin. Struct. Biol., 40 , pp. 128–135, 2016.

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Sawaya, Michael R; Rodriguez, Jose; Cascio, Duilio; Collazo, Michael J; Shi, Dan; Reyes, Francis E; Hattne, Johan; Gonen, Tamir; Eisenberg, David S

Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 113 (40), pp. 11232–11236, 2016.

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Bale, Jacob B; Gonen, Shane; Liu, Yuxi; Sheffler, William; Ellis, Daniel; Thomas, Chantz; Cascio, Duilio; Yeates, Todd O; Gonen, Tamir; King, Neil P; Baker, David

Accurate design of megadalton-scale two-component icosahedral protein complexes Journal Article

In: Science, 353 (6297), pp. 389–394, 2016.

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Hsia, Yang; Bale, Jacob B; Gonen, Shane; Shi, Dan; Sheffler, William; Fong, Kimberly K; Nattermann, Una; Xu, Chunfu; Huang, Po‐Ssu.; Ravichandran, Rashmi; Yi, Sue; Davis, Trisha N; Gonen, Tamir; King, Neil P; Baker, David

Design of a hyperstable 60-subunit protein icosahedron Journal Article

In: Nature, 535 (7610), pp. 136–139, 2016.

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Hattne, Johan; Shi, Dan; de la Cruz, Jason M; Reyes, Francis E; Gonen, Tamir

Modeling truncated pixel values of faint reflections in MicroED images Journal Article

In: J Appl Crystallogr, 49 (Pt 3), pp. 1029–1034, 2016.

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Shi, Dan; Nannenga, Brent L; de la Cruz, Jason M; Liu, Jinyang; Sawtelle, Steven; Calero, Guillermo; Reyes, Francis E; Hattne, Johan; Gonen, Tamir

The collection of MicroED data for macromolecular crystallography Journal Article

In: Nat Protoc, 11 (5), pp. 895–904, 2016.

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Meyer, Peter A; Socias, Stephanie; Key, Jason; Ransey, Elizabeth; Tjon, Emily C; Buschiazzo, Alejandro; Lei, Ming; Botka, Chris; Withrow, James; Neau, David; Rajashankar, Kanagalaghatta; Anderson, Karen S; Baxter, Richard H; Blacklow, Stephen C; Boggon, Titus J; Bonvin, Alexandre M J J; Borek, Dominika; Brett, Tom J; Caflisch, Amedeo; Chang, Chung-I; Chazin, Walter J; Corbett, Kevin D; Cosgrove, Michael S; Crosson, Sean; Dhe‐Paganon, Sirano; Cera, Enrico Di; Drennan, Catherine L; Eck, Michael J; Eichman, Brandt F; Fan, Qing R; Ferré‐D’Ámaré, Adrian R; Fromme, Christopher J; Garcia, Christopher K; Gaudet, Rachelle; Gong, Peng; Harrison, Stephen C; Heldwein, Ekaterina E; Jia, Zongchao; Keenan, Robert J; Kruse, Andrew C; Kvansakul, Marc; McLellan, Jason S; Modis, Yorgo; Nam, Yunsun; Otwinowski, Zbyszek; Pai, Emil F; Pereira, Pedro José Barbosa; Petosa, Carlo; Raman, C S; Rapoport, Tom A; Roll‐Mecak, Antonina; Rosen, Michael K; Rudenko, Gabby; Schlessinger, Joseph; Schwartz, Thomas U; Shamoo, Yousif; Sondermann, Holger; Tao, Yizhi J; Tolia, Niraj H; Tsodikov, Oleg V; Westover, Kenneth D; Wu, Hao; Foster, Ian; Fraser, James S; Maia, Felipe R N C; Gonen, Tamir; Kirchhausen, Tom; Diederichs, Kay; Crosas, Mercè; Sliz, Piotr

Data publication with the structural biology data grid supports live analysis Journal Article

In: Nat Commun, 7 , pp. 10882, 2016.

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Rodriguez, J A; Gonen, T

High-Resolution Macromolecular Structure Determination by MicroED, a cryo-EM Method Book Chapter

In: Methods in Enzymology, 579 , Chapter 14, pp. 369–392, 2016.

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2015

Rodriguez, Jose A; Ivanova, Magdalena I; Sawaya, Michael R; Cascio, Duilio; Reyes, Francis E; Shi, Dan; Sangwan, Smriti; Guenther, Elizabeth L; Johnson, Lisa M; Zhang, Meng; Jiang, Lin; Arbing, Mark A; Nannenga, Brent L; Hattne, Johan; Whitelegge, Julian; Brewster, Aaron S; Messerschmidt, Marc; Boutet, Sébastien; Sauter, Nicholas K; Gonen, Tamir; Eisenberg, David S

Structure of the toxic core of α-synuclein from invisible crystals Journal Article

In: Nature, 525 (7570), pp. 486–490, 2015.

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Bale, Jacob B; Park, Rachel U; Liu, Yuxi; Gonen, Shane; Gonen, Tamir; Cascio, Duilio; King, Neil P; Yeates, Todd O; Baker, David

Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression Journal Article

In: Protein Sci., 24 (10), pp. 1695–1701, 2015.

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Hattne, Johan; Reyes, Francis E; Nannenga, Brent L; Shi, Dan; de la Cruz, Jason M; Leslie, Andrew G W; Gonen, Tamir

MicroED data collection and processing Journal Article

In: Acta Crystallogr A Found Adv, 71 (Pt 4), pp. 353–360, 2015.

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Gonen, Shane; DiMaio, Frank; Gonen, Tamir; Baker, David

Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces Journal Article

In: Science, 348 (6241), pp. 1365–1368, 2015.

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2014

Huang, Po-Ssu; Oberdorfer, Gustav; Xu, Chunfu; Pei, Xue Y; Nannenga, Brent L; Rogers, Joseph M; DiMaio, Frank; Gonen, Tamir; Luisi, Ben; Baker, David

High thermodynamic stability of parametrically designed helical bundles Journal Article

In: Science, 346 (6208), pp. 481–485, 2014.

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Nannenga, Brent L; Shi, Dan; Hattne, Johan; Reyes, Francis E; Gonen, Tamir

Structure of catalase determined by MicroED Journal Article

In: Elife, 3 , pp. e03600, 2014.

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Russell, Alistair B; Wexler, Aaron G; Harding, Brittany N; Whitney, John C; Bohn, Alan J; Goo, Young Ah; Tran, Bao Q; Barry, Natasha A; Zheng, Hongjin; Peterson, Brook S; Chou, Seemay; Gonen, Tamir; Goodlett, David R; Goodman, Andrew L; Mougous, Joseph D

A type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism Journal Article

In: Cell Host Microbe, 16 (2), pp. 227–236, 2014.

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Wisedchaisri, Goragot; Park, Min-Sun; Iadanza, Matthew G; Zheng, Hongjin; Gonen, Tamir

Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE Journal Article

In: Nat Commun, 5 , pp. 4521, 2014.

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Nannenga, Brent L; Shi, Dan; Leslie, Andrew G W; Gonen, Tamir

High-resolution structure determination by continuous-rotation data collection in MicroED Journal Article

In: Nat. Methods, 11 (9), pp. 927–930, 2014.

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Nannenga, Brent L; Gonen, Tamir

Protein structure determination by MicroED Journal Article

In: Curr. Opin. Struct. Biol., 27 , pp. 24–31, 2014.

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Gonen, Tamir; Waksman, Gabriel

Editorial overview: Membranes: recent methods in the study of membrane protein structure Journal Article

In: Curr. Opin. Struct. Biol., 27 , pp. iv-v, 2014.

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King, Neil P; Bale, Jacob B; Sheffler, William; McNamara, Dan E; Gonen, Shane; Gonen, Tamir; Yeates, Todd O; Baker, David

Accurate design of co-assembling multi-component protein nanomaterials Journal Article

In: Nature, 510 (7503), pp. 103–108, 2014.

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Iadanza, Matthew G; Gonen, Tamir

A suite of software for processing MicroED data of extremely small protein crystals Journal Article

In: J Appl Crystallogr, 47 (Pt 3), pp. 1140–1145, 2014.

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Anderson, Thomas M.; Clay, Mary C.; Cioffi, Alexander G.; Diaz, Katrina A.; Hisao, Grant S.; Tuttle, Marcus D.; Nieuwkoop, Andrew J.; Comellas, Gemma; Maryum, Nashrah; Wang, Shu; Uno, Brice E.; Wildeman, Erin L.; Gonen, Tamir; Rienstra, Chad M.; Burke, Martin D.

Amphotericin forms an extramembranous and fungicidal sterol sponge Journal Article

In: Nat. Chem. Biol., 10 (5), pp. 400–406, 2014.

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2013

Shi, Dan; Nannenga, Brent L; Iadanza, Matthew G; Gonen, Tamir

Three-dimensional electron crystallography of protein microcrystals Journal Article

In: Elife, 2 , pp. e01345, 2013.

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Smith, Donelson F; Reichow, Steve L; Esseltine, Jessica L; Shi, Dan; Langeberg, Lorene K; Scott, John D; Gonen, Tamir

Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation Journal Article

In: Elife, 2 , pp. e01319, 2013.

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Gold, Matthew G; Gonen, Tamir; Scott, John D

Local cAMP signaling in disease at a glance Journal Article

In: J. Cell. Sci., 126 (Pt 20), pp. 4537–4543, 2013.

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Reichow, Stephen; Gonen, Tamir

Dynamic Modulation of Water Permeability in the Lens Aquaporin-0 Inproceedings

In: Proceedings of Microscopy & Microanalysis, pp. 50–51, 2013.

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Silverman, Julie M; Agnello, Danielle M; Zheng, Hongjin; Andrews, Benjamin T; Li, Mo; Catalano, Carlos E; Gonen, Tamir; Mougous, Joseph D

Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates Journal Article

In: Mol. Cell, 51 (5), pp. 584–593, 2013.

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Reichow, Steve L; Clemens, Daniel M; Freites, Alfredo J; Nemeth-Cahalan, Karin L; Heyden, Matthias; Tobias, Douglas J; Hall, James E; Gonen, Tamir

Allosteric mechanism of water-channel gating by Ca²⁺-calmodulin Journal Article

In: Nat. Struct. Mol. Biol., 20 (9), pp. 1085–1092, 2013.

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Zheng, Hongjin; Wisedchaisri, Goragot; Gonen, Tamir

Crystal structure of a nitrate/nitrite exchanger Journal Article

In: Nature, 497 (7451), pp. 647–651, 2013.

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Nannenga, Brent L; Iadanza, Matthew G; Vollmar, Breanna S; Gonen, Tamir

Overview of Electron Crystallography of Membrane Proteins: Crystallization and Screening Strategies Using Negative Stain Electron Microscopy Journal Article

In: Curr Protoc Protein Sci, 72 (1), pp. 17.15.1–17.15.11, 2013.

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Shi, Liang; Zheng, Hongjin; Zheng, Hui; Borkowski, Brian A; Shi, Dan; Gonen, Tamir; Jiang, Qiu-Xing

Voltage sensor ring in a native structure of a membrane-embedded potassium channel Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 110 (9), pp. 3369–3374, 2013, (Retracted).

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2012

Filbin, Megan E; Vollmar, Breanna S; Shi, Dan; Gonen, Tamir; Kieft, Jeffrey S

HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation Journal Article

In: Nat. Struct. Mol. Biol., 20 (2), pp. 150–158, 2012.

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Wisedchaisri, Goragot; Gonen, Tamir

Phasing Electron Diffraction Data by Molecular Replacement: Strategy for Structure Determination and Refinement Book Chapter

In: Electron Crystallography of Soluble and Membrane Proteins, 955 , Chapter 14, pp. 243–272, 2012.

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Gonen, Tamir

The Collection of High-Resolution Electron Diffraction Data Book Chapter

In: Electron Crystallography of Soluble and Membrane Proteins, 955 , Chapter 9, pp. 153–169, 2012.

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Stokes, David L; Ubarretxena-Belandia, Iban; Gonen, Tamir; Engel, Andreas

High-Throughput Methods for Electron Crystallography Book Chapter

In: Electron Crystallography of Soluble and Membrane Proteins, 955 , Chapter 15, pp. 273–296, 2012.

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Umbreit, Neil T.; Gestaut, Daniel R.; Tien, Jerry F.; Vollmar, Breanna S.; Gonen, Tamir; Asbury, Charles L.; Davis, Trisha N.

The Ndc80 kinetochore complex directly modulates microtubule dynamics Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 109 (40), pp. 16113–16118, 2012.

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Gonen, Shane; Akiyoshi, Bungo; Iadanza, Matthew G; Shi, Dan; Duggan, Nicole; Biggins, Sue; Gonen, Tamir

The structure of purified kinetochores reveals multiple microtubule-attachment sites Journal Article

In: Nat. Struct. Mol. Biol., 19 (9), pp. 925–929, 2012.

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Gonen, Tamir; Waksman, Gabriel

Recent progress in membrane protein structures and investigation methods Journal Article

In: Curr. Opin. Struct. Biol., 22 (4), pp. 467–468, 2012.

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Jiang, Qiu-Xing; Gonen, Tamir

The influence of lipids on voltage-gated ion channels Journal Article

In: Curr. Opin. Struct. Biol., 22 (4), pp. 529–536, 2012.

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King, Neil P; Sheffler, William; Sawaya, Michael R; Vollmar, Breanna S; Sumida, John P; André, Ingemar; Gonen, Tamir; Yeates, Todd O; Baker, David

Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy Journal Article

In: Science, 336 (6085), pp. 1171–1174, 2012.

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2011

Lo, Sheng-Ying; Brett, Christopher L; Plemel, Rachael L; Vignali, Marissa; Fields, Stanley; Gonen, Tamir; Merz, Alexey J

Intrinsic tethering activity of endosomal Rab proteins Journal Article

In: Nat. Struct. Mol. Biol., 19 (1), pp. 40–47, 2011.

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Gold, Matthew G; Reichow, Steve L; O'Neill, Susan E; Weisbrod, Chad R; Langeberg, Lorene K; Bruce, James E; Gonen, Tamir; Scott, John D

AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency Journal Article

In: EMBO Mol Med, 4 (1), pp. 15–26, 2011.

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132 entries « 2 of 3 »