196 entries « 1 of 4 »

2024

Lin, Jieye; Bu, Guanhong; Unge, Johan; Gonen, Tamir

An Updated Structure of Oxybutynin Hydrochloride

bioRxiv, 2024.

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Nicolas, William J.; Shiriaeva, Anna; Martynowycz, Michael W.; Grey, Angus C; Ruma, Yasmeen; Donaldson, Paul J; Gonen, Tamir

Structure of the lens MP20 mediated adhesive junction

bioRxiv, 2024.

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Unge, Johan; Lin, Jieye; Weaver, Sara J; Her, Ampon Sae; Gonen, Tamir

Compositional Analysis of Complex Mixtures using Automatic MicroED Data Collection

In: Advanced Science, 2024, ISSN: 2198-3844.

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Xia, Xian; Sung, Po-Yu; Martynowycz, Michael W.; Gonen, Tamir; Roy, Polly; Zhou, Z. Hong

RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells

In: Cell, 2024, ISSN: 0092-8674.

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Bu, Guanhong; Danelius, Emma; Wieske, Lianne H. E.; Gonen, Tamir

Polymorphic Structure Determination of the Macrocyclic Drug Paritaprevir by MicroED

In: Advanced Biology, vol. 8, iss. 5, pp. 2300570, 2024, ISSN: 2701-0198.

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Gillman, Cody; Bu, Guanhong; Danelius, Emma; Hattne, Johan; Nannenga, Brent; Gonen, Tamir

Eliminating the Missing Cone Challenge through Innovative Approaches

bioRxiv, 2024.

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Ruma, Yasmeen N; Bu, Guanhong; Gonen, Tamir

MicroED structure of the C11 cysteine protease Clostripain

bioRxiv, 2024.

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Lin, Jieye; Bu, Guanhong; Unge, Johan; Gonen, Tamir

Uncovering the Elusive Structures and Mechanisms of Prevalent Antidepressants

bioRxiv, 2024.

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2023

Lin, Jieye; Unge, Johan; Gonen, Tamir

Unraveling the Structure of Meclizine Dihydrochloride with MicroED

In: Adv Sci (Weinh), pp. e2306435, 2023, ISSN: 2198-3844.

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Walsh, Martin A; Nannenga, Brent L; Gonen, Tamir; Sexton, Patrick M; Wootten, Denise; Chiu, Wah; Sun, Fei; Carragher, Bridget; Potter, Clinton S; Agard, David; Burley, Stephen K

The next decade in structural biology

In: Structure, vol. 31, no. 11, pp. 1284–1288, 2023, ISSN: 1878-4186.

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Danelius, Emma; Bu, Guanhong; Wieske, Lianne H E; Gonen, Tamir

MicroED as a Powerful Tool for Structure Determination of Macrocyclic Drug Compounds Directly from Their Powder Formulations

In: ACS Chem Biol, 2023, ISSN: 1554-8937.

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Hattne, Johan; Clabbers, Max T. B.; Martynowycz, Michael W.; Gonen, Tamir

Electron counting with direct electron detectors in MicroED

In: Structure, 2023, ISSN: 0969-2126.

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Lin, Jieye; Unge, Johan; Gonen, Tamir

Distinct Conformations of Mirabegron Determined by MicroED

In: Adv Sci (Weinh), pp. e2304476, 2023, ISSN: 2198-3844.

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Bai, Xiao-Chen; Gonen, Tamir; Gronenborn, Angela M; Perrakis, Anastassis; Thorn, Andrea; Yang, Jianyi

Challenges and opportunities in macromolecular structure determination

In: Nat Rev Mol Cell Biol, 2023, ISSN: 1471-0080.

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Bu, G; Danelius, E; Wieske, L. H; Gonen, T

Polymorphic Structure Determination of the Macrocyclic Drug Paritaprevir by MicroED

bioRxiv, 2023.

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Lin, Jieye; Unge, Johan; Gonen, Tamir

Unraveling the Structure of Meclizine Dihydrochloride with MicroED

bioRxiv, 2023.

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Nannenga, Brent L.; Gonen, Tamir

The 2023 Structural Biology Summit at UCLA

In: Structure, vol. 31, pp. 1–2, 2023, ISSN: 0969-2126.

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Danelius, Emma; Bu, Guanhong; Wieske, Lianne; Gonen, Tamir

MicroED as a powerful tool for structure determination of macrocyclic drug compounds directly from their powder formulations

bioRxiv, 2023.

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Haymaker, Alison; Bardin, Andrey A.; Gonen, Tamir; Martynowycz, Michael W.; Nannenga, Brent L.

Structure determination of a DNA crystal by MicroED

In: Structure, 2023, ISSN: 0969-2126.

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Shiriaeva, Anna; Martynowycz, Michael W; Nicolas, William J; Cherezov, Vadim; Gonen, Tamir

MicroED structure of the human vasopressin 1B receptor

bioRxiv, 2023.

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Gonen, Tamir

Reflections on two decades of MicroED development

In: RefleXions, no. 2, pp. 7–8, 2023.

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Gillman, Cody; Nicolas, William J; Martynowycz, Michael W; Gonen, Tamir

Design and implementation of suspended drop crystallization

In: IUCrJ, vol. 10, iss. 4, 2023, ISSN: 2052-2525.

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Hattne, Johan; Clabbers, Max T. B.; Martynowycz, Michael W.; Gonen, Tamir

Electron-counting in MicroED

bioRxiv, 2023.

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Lin, Jieye; Unge, Johan; Gonen, Tamir

Distinct Conformations of Mirabegron Determined by MicroED

bioRxiv, 2023.

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Unge, Johan; Lin, Jieye; Weaver, Sara J; Her, Ampon Sae; Gonen, Tamir

Autonomous MicroED data collection enables compositional analysis

ChemRxiv, 2023.

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Nguyen, Chi; Lei, Hsiang-Ting; Lai, Louis Tung Faat; Gallenito, Marc J; Mu, Xuelang; Matthies, Doreen; Gonen, Tamir

Lipid flipping in the omega-3 fatty-acid transporter

In: Nat Commun, vol. 14, no. 1, pp. 2571, 2023, ISSN: 2041-1723.

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Gillman, Cody; Patel, Khushboo; Unge, Johan; Gonen, Tamir

The structure of the neurotoxin palytoxin determined by MicroED

bioRxiv, 2023.

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Haymaker, Alison; Bardin, Andrey A; Gonen, Tamir; Martynowycz, Michael W; Nannenga, Brent L

Structure determination of a DNA crystal by MicroED

bioRxiv, 2023.

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Gillman, Cody; Martynowycz, Michael; Nicolas, William Jules; Gonen, Tamir

Design and implementation of suspended drop crystallization

bioRxiv, 2023.

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Danelius, Emma; Porter, Nicholas J.; Unge, Johan; Arnold, Frances H.; Gonen, Tamir

MicroED Structure of a Protoglobin Reactive Carbene Intermediate

In: J. Am. Chem. Soc., 2023, ISSN: 1520-5126.

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Martynowycz, Michael W; Shiriaeva, Anna; Clabbers, Max T B; Nicolas, William J; Weaver, Sara J; Hattne, Johan; Gonen, Tamir

A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals

In: Nat Commun, vol. 14, iss. 1, no. 1, pp. 1086, 2023, ISSN: 2041-1723.

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Danelius, Emma; Patel, Khushboo; Gonzalez, Brenda; Gonen, Tamir

MicroED in drug discovery

In: Curr Opin Struct Biol, vol. 79, pp. 102549, 2023, ISSN: 1879-033X.

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2022

Clabbers, Max T. B.; Martynowycz, Michael W.; Hattne, Johan; Gonen, Tamir

Hydrogens and hydrogen-bond networks in macromolecular MicroED data

In: J Struct Biol X, vol. 6, pp. 100078, 2022.

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Danelius, Emma; Porter, Nicholas J.; Unge, Johan; Arnold, Frances H.; Gonen, Tamir

MicroED structure of a protoglobin reactive carbene intermediate

bioRxiv, 2022.

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Clabbers, Max T. B.; Martynowycz, Michael W.; Hattne, Johan; Nannenga, Brent L.; Gonen, Tamir

Electron-counting MicroED data with the K2 and K3 direct electron detectors

In: J Struct Biol, vol. 214, iss. 4, 2022.

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Martynowycz, Michael W.; Shiriaeva, Anna; Clabbers, Max T. B.; Nicolas, William J.; Weaver, Sara J.; Hattne, Johan; Gonen, Tamir

A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals

bioRxiv 2022, visited: 26.07.2022.

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Clabbers, Max T. B.; Martynowycz, Michael W.; Hattne, Johan; Nannenga, Brent L.; Gonen, Tamir

Electron-counting MicroED data with the K2 and K3 direct electron detectors

bioRxiv, 2022.

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Nguyen, Chi; Lei, Hsiang-Ting; Lai, Louis Tung Faat; Gallenito, Marc J.; Matthies, Doreen; Gonen, Tamir

Lipid flipping in the omega-3 fatty-acid transporter

bioRxiv 2022, visited: 01.06.2022.

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Martynowycz, Michael W.; Gonen, Tamir

Unlocking the potential of microcrystal electron diffraction

In: Physics Today, vol. 75, iss. 6, pp. 38–42, 2022.

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Martynowycz, Michael W; Clabbers, Max T B; Hattne, Johan; Gonen, Tamir

Ab initio phasing macromolecular structures using electron-counted MicroED data

In: Nat Methods, vol. 19, iss. 6, pp. 724–729, 2022, ISSN: 1548-7105.

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Porter, Nicholas; Danelius, Emma; Gonen, Tamir; Arnold, Frances

Biocatalytic Carbene Transfer Using Diazirines

ChemRxiv, 2022.

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Porter, Nicholas J; Danelius, Emma; Gonen, Tamir; Arnold, Frances H

Biocatalytic Carbene Transfer Using Diazirines

In: J Am Chem Soc, 2022, ISSN: 1520-5126.

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Clabbers, Max T. B.; Martynowycz, Michael W.; Hattne, Johan; Gonen, Tamir

Hydrogens and hydrogen-bond networks in macromolecular MicroED data

bioRxiv, 2022.

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Clabbers, Max T B; Shiriaeva, Anna; Gonen, Tamir

MicroED: conception, practice and future opportunities

In: IUCrJ, vol. 9, no. Pt 2, pp. 169–179, 2022, ISSN: 2052-2525.

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Gallenito, Marc J; Gonen, Tamir

Studying membrane proteins with MicroED

In: Biochem Soc Trans, vol. 50, no. 1, pp. 231–239, 2022, ISSN: 1470-8752.

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2021

Gonen, Tamir; Nannenga, Brent (Ed.)

cryoEM: Methods and Protocols

Springer US, 2021, ISBN: 978-1-0716-0965-1.

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Martynowycz, Michael W; Clabbers, Max T B; Unge, Johan; Hattne, Johan; Gonen, Tamir

Benchmarking the ideal sample thickness in cryo-EM

In: Proc Natl Acad Sci U S A, vol. 118, no. 49, 2021, ISSN: 1091-6490.

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Clark, Lisa J.; Bu, Guanhong; Nannenga, Brent L.; Gonen, Tamir

MicroED for the study of protein–ligand interactions and the potential for drug discovery

In: Nat Rev Chem, vol. 5, pp. 853–858, 2021.

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Martynowycz, Michael W.; Clabbers, Max T. B.; Hattne, Johan; Gonen, Tamir

Ab initio phasing macromolecular structures using electron-counted MicroED data

bioRxiv, 2021.

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Martynowycz, Michael W; Gonen, Tamir

Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED)

In: STAR Protoc, vol. 2, no. 3, pp. 100686, 2021, ISSN: 2666-1667.

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196 entries « 1 of 4 »