MicroED for the study of protein–ligand interactions and the potential for drug discovery. Nat Rev Chem, vol. 5, pp. 853–858, 2021.
Ligand Incorporation into Protein Microcrystals for MicroED by On-Grid Soaking. Structure, vol. 29, no. 1, pp. 88–95.e2, 2021.
cryoEM: Methods and Protocols. Springer US, 2021, ISBN: 978-1-0716-0965-1.
Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED. Structure, vol. 28, no. 10, pp. 1149–1159.e4, 2020.
Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER. Acta Crystallogr D Biol Crystallogr., vol. 76, no. 8, pp. 703-712, 2020.
MicroED with the Falcon III direct electron detector. IUCrJ, vol. 6, no. Pt 5, pp. 921–926, 2019.
The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination. ACS Cent Sci, vol. 4, no. 11, pp. 1587–1592, 2018.
Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system. Proc. Natl. Acad. Sci. U.S.A., vol. 115, no. 13, pp. 3362–3367, 2018.
Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J. Biol. Chem., vol. 293, no. 8, pp. 2888–2902, 2017.
Challenges in Structural Biology. HHMI Janelia Research Campus, 2017.
Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, vol. 353, no. 6297, pp. 389–394, 2016.
The Collection of High-Resolution Electron Diffraction Data. Electron Crystallography of Soluble and Membrane Proteins, vol. 955, Chapter 9, pp. 153–169, 2012.
The structure of purified kinetochores reveals multiple microtubule-attachment sites. Nat. Struct. Mol. Biol., vol. 19, no. 9, pp. 925–929, 2012.
AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency. EMBO Mol Med, vol. 4, no. 1, pp. 15–26, 2011.
The binding of cholera toxin to the periplasmic vestibule of the type II secretion channel. Channels (Austin), vol. 5, no. 3, pp. 215–218, 2011.
The prototypical H⁺/Galactose Symporter GalP Assembles into Functional Trimers. J. Mol. Biol., vol. 396, no. 3, pp. 593–601, 2010.
A Conformational Switch in Bacteriophage P22 Portal Protein Primes Genome Injection. Mol. Cell, vol. 29, no. 3, pp. 376–383, 2008.
Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature, vol. 438, no. 7068, pp. 633–638, 2005.
Aquaporin-0 Membrane Junctions Form Upon Proteolytic Cleavage. J. Mol. Biol., vol. 342, no. 4, pp. 1337–1345, 2004.
Galectin-3 Is Associated with the Plasma Membrane of Lens Fiber Cells. Investigative Ophthalmology and Visual Science, vol. 41, no. 1, pp. 199–203, 2000.
Unpublished cover art
HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. Nat. Struct. Mol. Biol., vol. 20, no. 2, pp. 150–158, 2012.
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy. Science, vol. 336, no. 6085, pp. 1171–1174, 2012.
Fragment-Based Phase Extension for Three-Dimensional Structure Determination of Membrane Proteins by Electron Crystallography. Structure, vol. 19, no. 7, pp. 976–987, 2011.
N-terminal domain of αB-crystallin provides a conformational switch for multimerization and structural heterogeneity. Proc. Natl. Acad. Sci. U.S.A., vol. 108, no. 16, pp. 6409–6414, 2011.
Structural Underpinnings of Nitrogen Regulation by the Prototypical Nitrogen-Responsive Transcriptional Factor NrpR. Structure, vol. 18, no. 11, pp. 1512–1521, 2010.
Structure of the cholera toxin secretion channel in its closed state. Nat. Struct. Mol. Biol., vol. 17, no. 10, pp. 1226–1232, 2010.
Noncanonical Binding of Calmodulin to Aquaporin-0: Implications for Channel Regulation. In: Structure, vol. 16, no. 9, pp. 1389–1398, 2008.